Provider review
A licensed provider reads your health intake and decides if PT-141 is right for you.
HomeBremelanotide / PT-141
For low sexual desire
PT-141, prescribed online.
PT-141 (bremelanotide) compounded by a licensed pharmacy, a licensed provider's review and free shipping in one plan. No office visit.
From $151/mo with the 12-month plan, same price with or without auto-refill
- Form
- Injection
- Active ingredient
- Bremelanotide
- Refill price
- Same as one-time
- Plans
- 1 to 12 months
- Licensed provider review
- Licensed compounding pharmacy
- Shipping included
- No subscription required
How would you like to pay?
Choose your plan
3-month plan$510
- $510 billed today
- Then $510 every 3 months
- Change or cancel refills anytime
- Licensed provider review
- Free discreet shipping
- Cancel refills anytime
Prescription treatment requires an online medical evaluation. A provider decides whether treatment is appropriate; approval is not guaranteed.
Licensed 503A pharmacyUSP <797> sterile compoundingIndependent provider reviewFree discreet shippingHIPAA-compliant
Product details
Bremelanotide / PT-141 at a glance
- Form
- Injection
- Active ingredient
- Bremelanotide
- Refill price
- Same as one-time
- Plans
- 1 to 12 months
- Prescribed by
- An independent licensed provider, after your online intake
- Prepared by
- A licensed compounding pharmacy
Your plan
Everything you need, in one plan
Your PT-141
Bremelanotide for injection, prepared by a licensed compounding pharmacy after approval.
Discreet shipping
Delivered to your door at no added cost.
Refills your way
Pay once or turn on auto-refill. The price is the same either way.
Label and study tools
Free tools to check the Vyleesi label limits, side-effect odds and study doses.
Order support
Help with your order and delivery when you need it.
How it works
Three steps, all online
- 1
Choose your plan
Pick 1, 3, 6 or 12 months. The price is the same with or without auto-refill.
- 2
Complete your health intake
Answer a private online questionnaire. A licensed provider reviews it.
- 3
Get it delivered
If prescribed, the pharmacy prepares your PT-141 and ships it to you free.
Why people choose it
What Bremelanotide is studied for
Each card links to the original study, with a tag for the kind of evidence behind it.
Approved label
Low desire in premenopausal women
FDA approved bremelanotide as Vyleesi for premenopausal women with acquired, generalized low sexual desire that causes distress.
Read the study Controlled human trialDesire scores
In 2 phase 3 trials with 1,267 premenopausal women, desire scores rose 0.5 and 0.6 points on a 1.2 to 6.0 scale with bremelanotide, versus 0.2 with placebo.
Read the study Controlled human trialDistress about low desire
In the same trials, distress about low desire fell 0.7 points on a 0 to 4 scale with bremelanotide, versus 0.4 with placebo.
Read the study Controlled human trialErections in men
In a 2004 crossover study, healthy men had measured erectile responses to PT-141 under the skin at doses above 1 mg. It is not approved for men.
Read the studyThe honest version
What the research does and doesn't show yet
Bremelanotide has 2 phase 3 trials and an FDA approval behind it, for one group of women. Here is what the trials found, and what they did not.
See every study we trackThe number of satisfying sexual events did not change versus placebo in either phase 3 trial.
Source40% of people on bremelanotide had nausea in the phase 3 trials, versus 1.3% on placebo. 8% stopped because of it.
SourceBlood pressure rises briefly after each dose, by up to 6 mmHg systolic, and usually returns to baseline within 12 hours.
SourceThe label does not cover men, women after menopause, or use to enhance sexual performance.
Source
FAQ
Questions, answered
The things people ask most before starting Bremelanotide.
How much does PT-141 cost?
$189 for 1 month, $510 for 3 months ($170 a month), $964 for 6 months ($160.67 a month) or $1,814 for 12 months ($151.17 a month). The price is the same with auto-refill or one-time. Shipping is included.
Do I need a prescription?
Yes. You complete an online health intake and a licensed provider decides whether PT-141 is right for you. Choosing a plan does not guarantee a prescription.
Is PT-141 FDA approved?
Bremelanotide is FDA approved only as Vyleesi, a 1.75 mg single-dose autoinjector. The PT-141 sold here is compounded by a licensed 503A pharmacy. It is not Vyleesi and is not FDA approved. FDA does not verify compounded drugs for safety, effectiveness or quality before they are sold.
How do I take it?
PT-141 in this plan is an injection. Your provider sets your dose and schedule. On the Vyleesi label, the dose is 1.75 mg under the skin at least 45 minutes before sex, no more than once in 24 hours and no more than 8 times a month.
Who is it approved for?
The Vyleesi label covers premenopausal women with acquired, generalized low sexual desire that causes distress. It does not cover men, women after menopause, or use to enhance sexual performance. Earlier work on erectile dysfunction in men did not lead to an approved product. Your provider decides if PT-141 fits you.
What are the side effects?
In the phase 3 trials, the most common were nausea (40% vs 1.3% on placebo), flushing (20.3% vs 0.3%) and headache (11.3% vs 1.9%). Nausea was most common after the first dose. Blood pressure also rises briefly after each dose.
Who should not use it?
The Vyleesi label says not to use it with uncontrolled high blood pressure or known heart disease. It can cause darker patches of skin, and it can slow how well some oral medicines, such as naltrexone, are absorbed. Tell your provider about every medicine you take.
How long until I notice a difference?
There is no set timeline. The Vyleesi label says to stop after 8 weeks if there is no improvement in desire. Your provider reviews how it is going.
Is there a subscription?
No. You can pay once for 1, 3, 6 or 12 months, or turn on auto-refill. The price is the same either way.