Editorial standards

Every page is built from a claims ledger: each factual statement is entered as a discrete claim, matched to a primary source fetched on a recorded date, stored with the exact supporting language, and graded by evidence type (FDA label statement, human RCT, uncontrolled human study, animal finding, in-vitro finding, regulatory record, review, journal record, or derived arithmetic). Statements about the approval, dosing and safety rules come only from the current VYLEESI label (SPL version 1, effective 2025-11-13) and FDA records. Study findings name their species in the study table, a human-trial chip is never placed on animal data, and where a cited trial has been retracted or flagged by its journal, the flag renders on the row. No physician or clinician has reviewed this site, and we do not claim medical review; what we claim is that every number resolves to its cited source, and the machine-readable ledger that proves it ships with the site.

Allowed sources: FDA (labels, Drugs@FDA, reviews, official FDA pages), DailyMed, PubMed-indexed peer-reviewed journals, ClinicalTrials.gov, and PubChem. Not allowed: clinic marketing pages, peptide vendors, wellness blogs, company press releases, and secondary aggregators. Where the honest answer is an absence (no approval for men, no head-to-head trial against Addyi, no approved vial format), we cite the record that documents the absence and say so plainly. Retracted work is cited only to document its retraction, never as evidence.

Each page displays its published and last-updated dates. We re-review this compound's pages when any of the following changes: the VYLEESI label (new SPL version), FDA action on NDA 210557, a journal action on any cited paper, or publication of a randomized human trial that would change a conclusion. Scheduled re-checks include re-resolving every citation link. Material changes get a dated note on the affected page.

If we got something wrong, we want it gone. Use the corrections link in the site footer and include the page URL and the claim you dispute. Verified corrections are made on the page with a dated note; claims that fail re-verification are removed from the ledger and from every surface that rendered them. We treat a citation that does not support its claim as the most serious defect this site can have.