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Bremelanotide / PT-141 / how it works

A clear path to a care decision.

Understand the exact product and plan, complete a private medical review, and know what happens after the clinician makes a decision.

How it works

Three steps, all online

  1. 1

    Choose your plan

    Pick 1, 3, 6 or 12 months. The price is the same with or without auto-refill.

  2. 2

    Complete your health intake

    Answer a private online questionnaire. A licensed provider reviews it.

  3. 3

    Get it delivered

    If prescribed, the pharmacy prepares your PT-141 and ships it to you free.

FAQ

Questions, answered

The things people ask most before starting Bremelanotide.

How much does PT-141 cost?

$189 for 1 month, $510 for 3 months ($170 a month), $964 for 6 months ($160.67 a month) or $1,814 for 12 months ($151.17 a month). The price is the same with auto-refill or one-time. Shipping is included.

Do I need a prescription?

Yes. You complete an online health intake and a licensed provider decides whether PT-141 is right for you. Choosing a plan does not guarantee a prescription.

Is PT-141 FDA approved?

Bremelanotide is FDA approved only as Vyleesi, a 1.75 mg single-dose autoinjector. The PT-141 sold here is compounded by a licensed 503A pharmacy. It is not Vyleesi and is not FDA approved. FDA does not verify compounded drugs for safety, effectiveness or quality before they are sold.

How do I take it?

PT-141 in this plan is an injection. Your provider sets your dose and schedule. On the Vyleesi label, the dose is 1.75 mg under the skin at least 45 minutes before sex, no more than once in 24 hours and no more than 8 times a month.

Who is it approved for?

The Vyleesi label covers premenopausal women with acquired, generalized low sexual desire that causes distress. It does not cover men, women after menopause, or use to enhance sexual performance. Earlier work on erectile dysfunction in men did not lead to an approved product. Your provider decides if PT-141 fits you.

What are the side effects?

In the phase 3 trials, the most common were nausea (40% vs 1.3% on placebo), flushing (20.3% vs 0.3%) and headache (11.3% vs 1.9%). Nausea was most common after the first dose. Blood pressure also rises briefly after each dose.

Who should not use it?

The Vyleesi label says not to use it with uncontrolled high blood pressure or known heart disease. It can cause darker patches of skin, and it can slow how well some oral medicines, such as naltrexone, are absorbed. Tell your provider about every medicine you take.

How long until I notice a difference?

There is no set timeline. The Vyleesi label says to stop after 8 weeks if there is no improvement in desire. Your provider reviews how it is going.

Is there a subscription?

No. You can pay once for 1, 3, 6 or 12 months, or turn on auto-refill. The price is the same either way.